- Location: Waterville, ME
- Nickname: Mules
- Conference New England Small College Athletic Conference
- Division: III
- Ballpark Coombs Field
Colby College has sponsored baseball since at least 1867. Dale Plummer has been the head baseball coach for Colby since 2007. Jack Coombs, a former major league pitcher and manager from the dead-ball era is the most prominent major leaguer to come from Colby.